Scoliosis Biomechanics

Adolescent idiopathic scoliosis is both the predominant spine deformity and the predominant form of scoliosis, affecting approximately 80% to 85% of all scoliosis patients. The reported prevalence typically ranges from 1%-3%. In 2010 and 2011 alone, US hospitals discharged more than 12,000 adolescent patients with idiopathic scoliosis, costing the nation more than $1.8 billion. As scoliosis affects some of the youngest orthopaedic patients who require permanency in their treatments, the instrumented-fusion should provide stabilization for many decades of life.

Current Research

At the JVL Research Center at Orthopaedic Institute for Children, biomechanical engineers and pediatric orthopaedic surgeons collaborate regularly to address clinical and surgical problems in the lab.

Our team has developed several in vitro models to simulate the surgical procedures that are performed to allow surgeons to compare the efficacy of various corrective maneuvers in the laboratory.

These in vitro models offer the advantage of testing surgical procedures pre-operatively. 


The faculty of the Implant Performance Laboratory includes Eddie Ebramzadeh, Ph.D., and Sophia Sangiorgio, Ph.D.


  1. Borkowski SL, Sangiorgio SN, Bowen RE, Scaduto AA, B. H, Bauer K, Ebramzadeh E: Strength of Thoracic Spine Under Simulated Direct Vertebral Rotation: A Biomechanical Study. Spine Deformity, 2016.
  2. Borkowski SL, Tamrazian E, Bowen RE, Scaduto AA, Ebramzadeh E, sangiorgio SN: Challenging the Conventional Standard for Thoracic Spine Range of Motion: A Systematic Review. The Journal of Bone and Joint Surgery American Volume Reviews, 2016.
  3. Borkowski SL, Sangiorgio SN, Bowen RE, Scaduto AA, Kwak J, Ebramzadeh E: Flexibility of thoracic spines under simultaneous multi-planar loading. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014.
  4. Sangiorgio SN, Borkowski SL, Bowen RE, Scaduto AA, Frost NL, Ebramzadeh E: Quantification of increase in 3-Dimensional spine flexibility following sequential Ponte osteotomies in a cadaveric model. Spine Deformity 2013, 1(3):171-178.