Joint Arthroplasty: Fixation

The JVL Research Center is recognized internationally for major contributions to the understanding of the effects of implant design features on fixation. The researchers developed the first composite synthetic femur for biomechanical testing in the 1980’s, now widely available. Numerous biomechanical models have been established for the evaluation of fixation of different types of implants.

Current Research

Various aspects of implant design and fixation have been evaluated using custom apparatuses built into servo-hydraulic load simulators. Some of the questions that have been addressed are:

  • What is the relative influence of proximal femoral stem geometry on initial fixation?
  • What is the influence of cement thickness on fixation of a femoral component?
  • How much proximal femoral bone is required to achieve stable fixation of a non-cemented implant?
  • What is the optimal surface finish for a cemented femoral stem?

Publications

  1. Lu Z, & Ebramzadeh E. (2019) Origins of material loss in highly worn acetabular cups of metal-on-metal total hip replacements. Journal of Orthopaedic Research 37: 143-150.
  2. Park SH, Lu Z, Hastings RS, Campbell PA, & Ebramzadeh E: Five hundred fifty-five retrieved metal-on-metal hip replacements of a single design show a wide range of wear, surface features, and histopathologic reactions. Clinical Orthopaedics and Related Research 2018, 476(2), 261-278.
  3. Sangiorgio, S. N., Ebramzadeh, E., Knutsen, A. R., Borkowski, S. L., Kalma, J. J., & Bengs, B. C. (2013). Fixation of non-cemented total hip arthroplasty femoral components in a simulated proximal bone defect model. The Journal of Arthroplasty, 28(9), 1618-1624.
  4. Sangiorgio, S. N., Longjohn, D. B., Dorr, L. D., & Ebramzadeh, E. (2011). Challenges in relating experimental hip implant fixation predictions to clinical observations. Journal of Biomechanics, 44(2), 235-243.
  5. Sangiorgio, S. N., Longjohn, D. B., Dorr, L. D., & Ebramzadeh, E. (2011). The influence of proximal stem geometry and surface finish on the fixation of a double-tapered cemented femoral stem. Journal of Biomechanics, 44(1), 22-27.
  6. Bengs, B. C., Sangiorgio, S. N., & Ebramzadeh, E. (2008). Less range of motion with resurfacing arthroplasty than with total hip arthroplasty: in vitro examination of 8 designs. Acta Orthopaedica, 79(6), 755-762.
  7. Sangiorgio, S. N., Longjohn, D. B., Lee, J. L., Alexander, J. D., Dorr, L. D., & Ebramzadeh, E. (2008). Simulation of extreme loads on the proximal femur for implant fixation assessment. Journal of Applied Biomaterials and Biomechanics, 6(2), 72-80.
  8. Sangiorgio, S. N., Ebramzadeh, E., Longjohn, D. B., & Dorr, L. D. (2004). Effects of dorsal flanges on fixation of a cemented total hip replacement femoral stem. Journal of Bone and Joint Surgery, 86(4), 813-820.
  9. Ebramzadeh, E., Sangiorgio, S. N., Longjohn, D. B., Buhari, C. F., & Dorr, L. D. (2004). Initial stability of cemented femoral stems as a function of surface finish, collar, and stem size. Journal of Bone and Joint Surgery, 86(1), 106-115.
  10. Ebramzadeh, E., Sangiorgio, S. N., Longjohn, D. B., Buhari, C. F., Morrison, B. J., & Dorr, L. D. (2003). Effects of total hip arthroplasty cemented femoral stem surface finish, collar and cement thickness on load transfer to the femur. Journal of Applied Biomaterials and Biomechanics, 1(1), 76-83.