Joint Arthroplasty: Clinical & Radiographic Outcome

The JVL research center has a longstanding heritage of collaborating with orthopaedic surgeons in addressing questions related to implant design and biomechanics, using clinical and radiographic outcome studies to compliment or enhance biomechanical models. Some of the clinical questions that have been addressed include:

  • What is the optimum cement thickness for a cemented femoral stem?
  • How are implant fixation interfaces influenced by a combination of stem geometry, stiffness, and wear characteristics?
  • How does implant position affect stresses at the interfaces and clinical outcome?



  1. Tan TL, Le Duff MJ, Ebramzadeh E, Bhaurla SK, Amstutz HC: Long-Term Outcomes of Liner Cementation into a Stable Retained Shell: A Concise Follow-up of a Previous Report. The Journal of bone and joint surgery American volume 2015, 97(11):920-924.
  2. Ebramzadeh, E., Campbell, P.A., Takamura, K.M., Lu, Z., Sangiorgio, S.N., Kalma, J.J., De Smet, K., Amstutz, H.C.: “Failure Modes of 433 Metal-on-Metal Hip Implants: How, Why and Wear.” Orthop Clin North Am. 2011 Apr;42(2):241-50.
  3. Beaule PE, Lee JL, Le Duff MJ, Amstutz HC, Ebramzadeh E: Orientation of the femoral component in surface arthroplasty of the hip. A biomechanical and clinical analysis. The Journal of bone and joint surgery American volume 2004, 86-A(9):2015-2021.
  4. Ebramzadeh, E., Normand, PL, Sangiorgio, S.N., Llinas, A., Gruen, T.A., McKellop, H.A., Sarmiento, A. “Long-term radiographic changes in cemented total hip arthroplasty with six designs of femoral components.” Biomaterials, 2003. Aug;24(19):3351-63.
  5.  Ebramzadeh E, Sarmiento A, McKellop HA, Llinas A, Gogan W: The cement mantle in total hip arthroplasty. Analysis of long-term radiographic results. The Journal of bone and joint surgery American volume 1994, 76(1):77-87.