Joint Arthroplasty: Clinical & Radiographic Outcome

The JVL research center has a longstanding heritage of collaborating with orthopaedic surgeons in addressing questions related to joint replacement implant design and biomechanics, using clinical and radiographic outcome studies to compliment or enhance biomechanical models. Some of the clinical questions that have been addressed include:

Noteable Studies

  • What is the optimum cement thickness for a cemented femoral stem?
  • How are implant fixation interfaces influenced by a combination of stem geometry, stiffness, and wear characteristics?
  • How does implant position affect stresses at the interfaces and clinical outcome?


  1. Park SH, Lu Z, Hastings RS, Campbell PA, & Ebramzadeh E: Five hundred fifty-five retrieved metal-on-metal hip replacements of a single design show a wide range of wear, surface features, and histopathologic reactions. Clinical Orthopaedics and Related Research 2018, 476(2), 261-278.
  2. Tan, T. L., Le Duff, M. J., Ebramzadeh, E., Bhaurla, S. K., & Amstutz, H. C. (2015). Long-term outcomes of liner cementation into a stable retained shell: a concise follow-up of a previous report. JBJS, 97(11), 920-924.
  3. Amstutz, H. C., Takamura, K. M., Ebramzadeh, E., & Le Duff, M. J. (2015). Highly cross-linked polyethylene in hip resurfacing arthroplasty: long-term follow-up. Hip International, 25(1), 39-43.
  4. Tan, T. L., Ebramzadeh, E., Campbell, P. A., Al-Hamad, M., & Amstutz, H. C. (2014). Long-term outcome of a metal-on-polyethylene cementless hip resurfacing. The Journal of Arthroplasty, 29(4), 802-807.
  5. Yoon, J. P., Le Duff, M. J., Johnson, A. J., Takamura, K. M., Ebramzadeh, E., & Amstutz, H. C. (2013). Contact patch to rim distance predicts metal ion levels in hip resurfacing. Clinical Orthopaedics and Related Research®, 471(5), 1615-1621.
  6. Sangiorgio SN, Ebramzadeh E, Knutsen AR, Borkowski SL, Kalma JJ, Bengs BC: Fixation of non-cemented total hip arthroplasty femoral components in a simulated proximal bone defect model. The Journal of Arthroplasty 2013, 28(9), 1618-1624.
  7. Amstutz, H. C., Ebramzadeh, E., Sarkany, A., Le Duff, M., & Rude, R. (2004). Preservation of bone mineral density of the proximal femur following hemisurface arthroplasty. Orthopedics, 27(12), 1266-1271.
  8. Beaulé, P. E., Lee, J. L., Le Duff, M. J., Amstutz, H. C., & Ebramzadeh, E. (2004). Orientation of the femoral component in surface arthroplasty of the hip: a biomechanical and clinical analysis. Journal of Bone and Joint Surgery, 86(9), 2015-2021.
  9. Ebramzadeh, E., Normand, P. L., Sangiorgio, S. N., Llinás, A., Gruen, T. A., McKellop, H. A., & Sarmiento, A. (2003). Long-term radiographic changes in cemented total hip arthroplasty with six designs of femoral components. Biomaterials, 24(19), 3351-3363.
  10. Ebramzadeh, E., Sangiorgio, S. N., Lattuada, F., Kang, J. S., Chiesa, R., McKellop, H. A., & Dorr, L. D. (2003). Accuracy of measurement of polyethylene wear with use of radiographs of total hip replacements. Journal of Bone and Joint Surgery, 85(12), 2378-2384.
  11. Ebramzadeh, E., Sarmiento, A., McKellop, H. A., Llinas, A., & Gogan, W. (1994). The cement mantle in total hip arthroplasty. Analysis of long-term radiographic results. Journal of Bone and Joint Surgery, 76(1), 77-87.
  12. McKellop, H. A., Sarmiento, A., Schwinn, C. P., & Ebramzadeh, E. (1990). In vivo wear of titanium-alloy hip prostheses. Journal of Bone and Joint Surgery. American volume, 72(4), 512-517.